Primary Amenorrhea

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Primary amenorrhea is defined as either 1. no period by age 14 in the absence of growth and development of secondary sexual characteristics; or 2. no period by age 16 regardless of the presence of normal growth and development of secondary sexual characteristics.

Investigations

History

  • pubertal milestones
  • weight changes
  • psychological dysfunction
  • emotional stress
  • nutrition
  • exercise
  • medication
  • chronic disease
  • family history

Physical

  • stature
  • secondary sexual characteristics
  • reproductive tract anomalies
  • nutritional status
  • galactorrhea [1]
  • hirsutism
  • CNS disease

Tests