Peutz-Jeghers polyp

From IKE
Jump to: navigation, search

Peutz-Jeghers polyps are hamartomatous colorectal polyps with a distinctive smooth muscular framework which distinguishes them from other polyps. They are found more often in the small bowel than the large bowel.

Peutz-Jeghers polyposis is another autosomal dominantly inherited syndrome with polyps occurring most commonly in the small bowel but also in the stomach and colon. It is associated with mucocutaneous pigmentation with spots on the lips, buccal mucosa and skin. Patients with PJ polyposis are at increased risk for malignancy, not only in the gastrointestinal tract but also in the ovary, breast, pancreas and lung.