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Ovulation is the ultimate goal of the menstrual cycle in the reproductive female, during which oocytes are released from the ovaries. Ovulatory status can be determined by:

  • Regular 21 - 35 day cycles
  • Presence of suggestive symptoms (mittelschmerz, pre-menstrual, or dysmenorrhea)
  • Presence of biphasic basal body temperature
  • Positive serum progesterone
  • Endometrial histology (secretory as opposed to proliferative)

Though all of these factors should be taken into account to evaluate ovulatory status, the first two are responsible for 95% of the evaluation. However, the only 100% effective method of proving ovulation is pregnancy.