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Hepatoblastomas are a very rare liver cancer, though it is the most common primary malignant liver tumour in children. Most of the children affected are under the age of 2, and they occasionally present with precocious puberty resulting from ectopic gonadotropin production. Usually, however, the disease is detected as a result of failing systemic health (failure to thrive) and a right upper quadrant mass.

This cancer is mostly resectable, radiation sensitive and chemotherapy sensitive. The long term survival is 15-35%.