The gall bladder is a pear-shaped bag that sits slightly on the transverse colon in the abdominal cavity. The gall bladder's body is related to the second part of the duodenum, and it contacts the anterior abdominal wall at the transpyloric plane. Between meals, the gall bladder works to concentrate and store bile.
The gall bladder consists of three parts, the fundus, body and neck. The fundus is the blind end of the sac, and projects anteriorly, beyond the inferior border of the liver, to contact the anterior abdominal wall at the junction of the right linea semilunaris and the costal arch. Here, it may be palpable when distended or inflamed (Murphy's sign). The fundus often rests on the transverse colon.
The neck is continuous with the cystic duct, and is related to the first part of the duodenum.