File:Janeway-8.19.gif

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Janeway Figure 8.19. High-affinity IL-2 receptors are three-chain structures that are produced only on activated T cells. On resting T cells, the β and γ chains are expressed constitutively. They bind IL-2 with moderate affinity. Activation of T cells induces the synthesis of the α chain and the formation of the high-affinity heterotrimeric receptor. The β and γ chains show similarities in amino acid sequence to cell-surface receptors for growth hormone and prolactin, both of which also regulate cell growth and differentiation.

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current19:56, 10 March 2004Thumbnail for version as of 19:56, 10 March 2004219 × 207 (6 KB)Tarek (talk | contribs)Janeway Figure 8.19. High-affinity IL-2 receptors are three-chain structures that are produced only on activated T cells. On resting T cells, the β and γ chains are expressed constitutively. They bind IL-2 with moderate affinity. Activation of
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