File:Janeway-6.7.gif

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Janeway Figure 6.7. The B-cell receptor complex is made up of cell-surface immuno-globulin with one each of the invariant proteins Igα and Igβ. The immunoglobulin recognizes and binds antigen but cannot itself generate a signal. It is associated with antigen-nonspecific signaling molecules Igα and Igβ. These each have a single immunoreceptor tyrosine-based activation motif (ITAM), shown as a yellow segment, in their cytosolic tails that enables them to signal when the B-cell receptor is ligated with antigen. Igα and Igβ are disulfide-linked and associated with the heavy chains, but it is not known which binds to the heavy chain.

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current19:47, 10 March 2004 (11 KB)Tarek (talk | contribs)Janeway Figure 6.7. The B-cell receptor complex is made up of cell-surface immuno-globulin with one each of the invariant proteins Igα and Igβ. The immunoglobulin recognizes and binds antigen but cannot itself generate a signal. It is associate
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