Chorionic villus sampling

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Chorionic villus sampling is a a technique used in fetal screening during a pregnancy of the reproductive female, used for prenatal diagnosis in the first trimester (10-12 wks). Chorionic villi are aspirated in a syringe and cultured short-term and long-term in the laboratory. Karyotypes are obtained from both cultures, although those based on the long-term specimen are more accurate [1].

This technique can be carried out trans-vaginaly or trans-abdominally. The risk of fetal loss is 1% over the background 3% rate of loss.