Again, what are the targets and actions?
- Poorly understood targets and actions
- difference in pharmacological dose (and effects) and physiological dose (and effects)
- Effects on two well-studied organs:
- suppresses reabsorption of bone by inhibiting osteoclasts
- release calcium and phosphorous into blood
Is there a real physiological role for this hormone?
- At best, it has a minor role in regulating blood calcium
- Decreased calcitonin =/= decreased or abnormal serum calcium